0704-883-0675     |      dataprojectng@gmail.com

COMPARATIVE EVALUATION OF THE ASCORBIC ACID CONTENT OF MINERAL ASCORBATE AND ASCORBIC ACID TABLETS MARKETED IN ZARIA

  • Project Research
  • 1-5 Chapters
  • Abstract : Available
  • Table of Content: Available
  • Reference Style: APA
  • Recommended for : Student Researchers
  • NGN 3000

ABSTRACT

The ascorbic acid content of mineral ascorbate and six brands of ascorbic acid tablets marketed in Zaria with brand names Calcium ascorbate, Ascorbion, Emvit C, Ascorvite, Topcee, Bioracee and Sofa C respectively were comparatively evaluated using four methods. These include titrimetric method of British pharmacopoiea 2009, sodium thiosulphate titrimetric method, Ultra violet spectrophotometric method employing stabilizers and a newly developed 2,4- dinitrophenyl hydrazine method. The developed method was validated and the analyte showed an absorption maxima at 527nm and a percentage recovery of 97.4%. Beer‘s law was obeyed in the concentration range of 5ug to 25ug/ml, giving a regression equation of y= 0.041x + 0.032 and a correlation coefficient of 0.9910. The percentage content of ascorbic acid in Calcium ascorbate, Ascorbion, EmvitC, Ascorvite, Topcee, Bioracee, and SofaC in the Ultra violet spectroscopy method using stabilizers were 108.2%, 29.7%, 26.3%, 33%, 66.7%, 46.7%, 27.948% respectively. The values obtained from the sodium thiosulphate titrimetric method were 95.6%, 98.30%, 101.90%, 94.86%, 94.18%, 98.89% and 100.02% respectively. The results obtained from the B.P 2009 titrimetric method were 100.58%, 102.49%, 108.51%, 100.12%, 79.29%, 102.05% and 104.84% respectively, while that of the modified 2,4-dinitrophenyl hydrazine method were 100.47%, 101.99%, 107.898%, 99.83%%, 78.02%, 101.97%, 104.96% respectively. These results obtained showed that the UV spectrophotometric method gave values below the normal range. The values from the sodium thiosulphate titrimetric method was within the normal range but does not compare favourably with the official method, whereas the values for the modified 2,4 dinitrophenylhydrazine method and that of the B.P 2009 titrimetric method were both within the normal range and compared favourably with each other. Both results subjected to Student‘s T-testing showed no significant difference at P value 95% confidence interval (p=0.05). The B.P 2009 titrimetric method showed that there is one substandard product, which is Sofa C on the basis that it has a percent label claim not within 90±5%. The findings of this work further showed that the newly modified method can be used as a substitute for the official method.




FIND OTHER RELATED TOPICS


Related Project Materials

ANTIFUNGAL ACTIVITY OF LOCALLY MADE SOAP ON DERMATOPHYTES ISOLATED FROM BARBING EQUIPMENT

ABSTRACT

The comparative study on the effect of the locally made black soap and Dudu osun soap on dermatophytes isolated...

Read more
INSTRUCTIONAL PROBLEMS ASSOCIATED WITH POOR PERFORMANCE IN SECONDARY SCHOOLS BY TECHNICAL EDUCATION STUDENTS

NTS

 

ABSTRACT

In recent times, there have been numerous cases of student&rsqu...

Read more
THE EFFECT OF HUMAN RESOURCE DEVELOPMENT ON EMPLOYEE PRODUCTIVITY

ABSTRACT

This project is on ‘’the assessment of the effect of human resource development on employee product...

Read more
EVALUATION OF NIGERIA CAPITAL MARKET STRUCTURE AND DEVELOPMENT (A CASE STUDY OF NIGERIA STOCK EXCHANGE NSE)

BACKGROUND OF THE STUDY    

The capital market performs for the economy, at the long-term end of the...

Read more
AN ASSESSMENT OF THE RELATIONSHIP BETWEEN EDUCATIONAL FUNDING AND ECONOMIC GROWTH IN NIGERIA

ABSTRACT

This research work was conducted to examine the Respondents’ responses on the assessment...

Read more
EFFECT OF POSITIVE REINFORCEMENT COUNSELLING TECHNIQUE ON ABSENTEEISM AMONG SECONDARY SCHOOL STUDENTS IN BAKORI LOCAL GOVERNMENT, KATSINA STATE, NIGERIA

ABSTRACT

This study examined the effect of positive reinforcement counselling technique on absenteeism among secondary school students in...

Read more
IMPACTOF INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) ON RADIO NEWS REPORTING (A STUDY OF ATLANTIC FM UYO)

Background of the Study

Broadcasting has been at the forefront of many technological changes, mostly in digitalization and enhancement of...

Read more
INVESTIGATION OF THE WIDESPREAD AND MANAGEMENT OF EXAMINATION MALPRACTICES IN NIGERIA

                       &...

Read more
CAUSES OF ROAD ACCIDENT

ABSTRACT

This study was undertaken to examine the perceived causes of road accident among automobile road users using Ij...

Read more
ETHICAL CONSIDERATIONS IN FINANCIAL MANAGEMENT

This research explores ethical considerations in financial management. Objectives include identifying common ethical issues in financial management...

Read more
Share this page with your friends




whatsapp